Adenosine 3′,5′-Monophosphate in Glial Tumor Cells
نویسندگان
چکیده
منابع مشابه
Control of adenosine monophosphate catabolism in mouse ascites tumor cells.
Experiments were conducted to determine whether en ergy charge, (ATP + 1/2 ADP)/(ATP + ADP + AMP) (in which AMP, ADP, and ATP are adenosine mono-, di-, and triphosphate, respectively) or intracellular inorganic phosphate was the primary regulator of the rate of aden osine 5 -monophosphate (AMP) catabolism in intact mouse ascites tumor cells. Hyperdiploid (ELD) and tetraploid (ELT/B1) cell suspe...
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Adrenergic stimulation of LRM55 glial cells results in the release of the neuroactive amino acid taurine. The present study characterizes the receptors involved in taurine release and shows that taurine release is mediated by cyclic adenosine 3’,5’-monophosphate (CAMP). ,&Receptors in LRM55 cells were first characterized by [‘251]iodohydroxybenzylpindolol binding. Binding was stereospecific and...
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The adenine nucleotides, 5'-AMP and 3',5'-cyclic AMP block L cells in the S-phase of the cell cycle. The intracellular level of cyclic AMP is reduced after incubation of cells with 5'-AMP, and rates of uridine transport are increased after incubation with either 5'-AMP or cyclic AMP. On the contrary, cyclic AMP levels are increased and uridine transport decreased in cells treated with an inhibi...
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The cytostatic effects of puromycm, [(6)N]O(2')-dibutyryl 3',5'-adenosine monophosphate, and adenosine on asynchronous and synchronous cultures of the murine mastocytoma, P815Y, have been studied. Cell growth was arrested after a minimum of one further division. A model is proposed for the inhibition of cell division in which the periods of inhibition and growth arrest are separated in time by ...
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Cyclic adenosine monophosphate (cAMP) controls the physiological response to many diverse extracellular stimuli. To maintain signal specificity, cAMP-mediated signaling is finely tuned by means of a complex array of proteins that control the spatial and temporal dynamics of the second messenger within the cell. To unravel the way a cell encodes cAMP signals, new biosensors have recently been in...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1973
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(19)44062-3